ABSTRACT
From January 1998 to December 2004, 207 out of 1125 samples were HSV isolation positive and typed. Two groups of patients, Thai and foreigner, as well as site of infection, non-genital and genital area, were identified. The prevalence of non-genital HSV-1 infection from 27 samples of Thai patients was 81.84%. Out of 180 genital samples, 39.02% HSV-1 and 43.09% HSV-2 from 123 Thai patients and 36.84% HSV-1 and 49.12% HSV-2 of 57 foreigner patients were determined. Moreover mixed infection of HSV-1 and HSV-2 was found in both Thai and foreigner groups, 17.89% and 14.04%, respectively. The prevalence of genital HSV-1 infection in Thai patients chronologically increases from 1.6% to 56.91% from of 1985 to 2004. Increase of HSV-1 genital infection and mixed HSV-1 and HSV-2 infection in Thai people might probably be due to changing of sexual behavior in the AIDS era.
Subject(s)
Antibodies, Viral/isolation & purification , Female , Fluorescent Antibody Technique, Indirect , Health Surveys , Herpes Genitalis/diagnosis , Herpesvirus 1, Human/immunology , Herpesvirus 2, Human/immunology , Hospitals, Urban , Humans , Laboratories, Hospital , Male , Prevalence , Sexual Behavior , Thailand/epidemiologyABSTRACT
Respiratory syncytial virus (RSV) is the single most important cause of lower respiratory tract infection during infancy and early childhood worldwide including Thailand. The magnitude as well as the intensity of both infection and host response to the RSV infection determine the severity of disease. To determine the presence of anti-RSV IgG in children of different age groups, 124 serum samples were randomly collected from healthy children aged 6 months to 5 years. All of them were assayed for anti-RSV IgG using a commercial ELISA kit. The mean prevalence rate was found to be 68.91%. The prevalence increased with age: from 6 to 11 months, 11.76%; from 12 to 17 months, 41.67%; from 18 to 23 months, 60.87%; from 24 to 29 months, 88.24%; from 30 to 35 months, 78.57%; from 36 to 41 months, 94.44% and from 42 to 60 months, 100%. The amount of anti-RSV IgG among the groups was significantly different (p = 0.006). No sexual preponderance was found. RSV infection commonly occurred in children aged 12 to 29 months. All children older than 5 years had experienced a RSV infection.
Subject(s)
Age Distribution , Antibodies, Viral/blood , Child, Preschool , Female , Humans , Immunoglobulin G/blood , Infant , Male , Respiratory Syncytial Virus Infections/diagnosis , Respiratory Syncytial Virus, Human/immunology , Seroepidemiologic Studies , Sex Distribution , Thailand/epidemiologyABSTRACT
The prevalence of antibody to human parvovirus B19 in 128 Thai healthy young adults was measured. Antibodies of the immunoglobulin G (IgG) class were investigated in serum samples of 51 males and 77 females aged 18-24 years (mean 19.83; SD 1.07) by a commercial enzyme-linked immunosorbent assay (ELISA) using high specific recombinant parvovirus B 19 antigen. Only 14 out of 128 (10.94%) sera were found positive, including 6 males and 8 females. No sex preponderance was observed. The amount of antibody calculated as antibody index was not statistically significant difference between genders.